Modulation of cell membrane area in renal collecting tubules by corticosteroid hormones.
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چکیده
منابع مشابه
Modulation of cell membrane area in renal collecting tubules by corticosteroid hormones
Isolated renal cortical collecting tubules obtained from rabbits treated chronically with desoxycorticosterone acetate (DOCA) have been found to possess elevated transepithelial potential differences and a greatly increased capacity for ion transport. Structural exmination of tubules from rabbits exposed to either DOCA or dexamethasone for 11--18 d reveals a marked increase in basolateral cell ...
متن کاملPaths of Transtubular Water Flow in Isolated Renal Collecting Tubules
The cells of perfused rabbit collecting tubules swell and the intercellular spaces widen during osmotic flow of water from lumen to bath induced by antidiuretic hormone (ADH). Ouabain had no influence on these changes. In the absence of net water flow intercellular width was unaffected when tubules were swollen in hypotonic external media. Therefore, during ADH-induced flow widening of intercel...
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In 1943, while I was in the U. S. Army, a young soldier was referred to me because of gross, painless, total hematuria and a peculiarly abnormal excretion urogram. Except for this gross abnormality which looked as though a bunch of grapes were attached to each minor calyx (Fig. la and lb), no explanation could be found for his hematuria. There was no evidence of calculous disease. There was no ...
متن کاملOsmosis in Cortical Collecting Tubules
This paper reports a theoretical analysis of osmotic transients and an experimental evaluation both of rapid time resolution of lumen to bath osmosis and of bidirectional steady-state osmosis in isolated rabbit cortical collecting tubules exposed to antidiuretic hormone (ADH). For the case of a membrane in series with unstirred layers, there may be considerable differences between initial and s...
متن کاملBicarbonate secretion by rabbit cortical collecting tubules in vitro.
We previously reported that rabbit renal cortical collecting tubules can secrete bicarbonate in vitro (i.e., there can be net transport from bath to lumen, causing the concentration in the lumen to increase). Net bicarbonate secretion was observed most often when rabbits had been pretreated with NaHCO(3) and were excreting alkaline urine before being killed for experiments. The purpose of the p...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1979
ISSN: 0021-9525,1540-8140
DOI: 10.1083/jcb.81.2.439